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SIGNATURE™ SYSTEM: THE SOLUTION THAT'S JUST FOR YOU.

Personalized Approach to Knee Replacement

If you think the Oxford® Partial Knee sounds good, wait until you hear this. Every Oxford knee is now available with an added bonus: personalized implant positioning. We call it the Signature** system, and it's the knee replacement technique that's based on your specific anatomy. Using MRI technology and patient-matched guides, the system helps surgeons plan for the alignment of your Oxford Partial Knee. It's the personalized approach that's just for you, from Zimmer Biomet.

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How does it work?

Instead of relying on two-dimensional x-rays to plan your surgery, the Signature™ system uses an MRI of your knee in conjunction with computer software to create a 3-D image of your unique knee joint. The MRI is also used to create custom femoral (thighbone) and tibial (shinbone) positioning guides that fit directly onto your unique anatomy. With the combination of the MRI and Signature™ positioning guides, your surgeon has access to a greater level of detail and precision for implant positioning and alignment before the procedure. The result? Patient-specific positioning of your knee implant.

Key Advantages of the Signature System:

  • Precise, personalized approach to knee replacement
  • Based on your specific anatomy
  • Uses 3-D MRI technology instead of 2-D x-rays
  • Patient-matched guides help surgeons with implant positioning

WHAT MAKES SIGNATURE SURGERY SO UNIQUE?

Before Surgery

With the Signature system for the Oxford Partial Knee, your preoperative experience will be similar to most total knee patients, with one exception. An MRI of your affected leg will be required. A typical MRI scan lasts about 20 minutes. The scan will be performed only on your hip, knee and ankle, so your head will remain outside the machine. The MRI is used for preoperative planning by your surgeon and for the design and manufacture of the Signature™ personalized positioning guides that will be used during your partial knee replacement.

During Surgery

During surgery, there are significant differences between traditional and Signature knee replacement techniques.

Traditional Knee Replacement - During traditional knee replacement, metal instruments are used to remove the damaged bone and cartilage, confirm implant sizing, and establish proper implant positioning and alignment on the bone. Additionally, instruments are sometimes placed inside the femur (thighbone) and/or tibia (shinbone) to assist with implant alignment and positioning.

  • Metal instruments establish implant position and alignment
  • Metal rods are sometimes placed inside the bone canal

Signature Knee Replacement - With the Signature system, custom guides are placed directly onto your unique anatomy to assist the surgeon with implant alignment and positioning. These personalized guides are created from the 3-D MRI of your knee.

  • Custom guides are placed directly onto your knee anatomy
  • Custom guides have implant position and alignment built into their design

**A collaborative partnership with Materialise, N.V.

Find a Doctor

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Need assistance? Please call: 1-800 HIP-KNEE (1-800-447-5633)

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Not all patients are candidates for partial knee replacement. Only your orthopedic surgeon can tell you if you're a candidate for joint replacement surgery, and if so, which implant is right for your specific needs. You should discuss your condition and treatment options with your surgeon. The Oxford®Partial Knee is intended for use in individuals with osteoarthritis or avascular necrosis limited to the medial compartment of the knee and is intended to be implanted with bone cement. The Oxford®Knee is not indicated for use in the lateral compartment. Potential risks include, but are not limited to, loosening, dislocation, fracture, wear, and infection, any of which can require additional surgery.

Zimmer Biomet is a manufacturer of orthopedic implants and does not practice medicine. Only an orthopedic surgeon can determine what treatment is appropriate. Individual results of total joint replacement may vary. The life of any implant will depend on your weight, age, activity level, and other factors. For more information on risks, warnings, and possible adverse effects, see the Patient Risk Information section found within ZimmerBiomet.com. Always ask your doctor if you have any questions regarding your particular condition or treatment options.

Oxford® and Signature™ are trademarks of Zimmer Biomet or its subsidiaries unless otherwise indicated.

References

  1. Lombardi, A. et al. Is Recovery Faster for Mobile-bearing Unicompartmental than Total Knee Arthroplasty? Clinical Orthopedics and Related Research. 467:1450-57.2009
  2. Hopper, PG.,Leach, WJ. Participation in sporting activities following total knee replacement: total versus unicompartmental. Knee Surgery Sports Traumatology Arthroscopy.2008.16:973-979
  3. Hall et al. Unicompartmental Knee Arthroplasty (Alias Uni-Knee)-An Overview with Nursing Implications. Orthopedic Nursing. 2004; 23(3):163-171
  4. Price, AJ, et al. Simultaneous in vitro measurement of patellofemoral kinematics and forces following Oxford medial unicompartmental knee replacement. JBJS (Br). 2006; 88-B; 12: 1591-1595.
  5. Data on File. Cobb, J, et al. Functional Assessment of knee arthroplasty using an instrumented treadmill. Imperial College of London. March 8, 2012. Presentation.
  6. Argenson, J., et al. Polyethylene Wear in Meniscal Knee Replacement. A One to Nine-year Retrieval. Analysis of the Oxford Knee. The Journal of Bone and Joint Surgery. 1992; 74-B(2):228-32.
  7. Ng, VY, et al. Improved Accuracy of Alignment With Patient Specific Positioning Guides Compared with Manual Instrumentation in TKA. Clinical Orthopaedics and Related Research. August 2011. Published Online.
  8. Murray, D. et al. The Oxford Medial Unicompartmental Arthroplasty. A Ten-Year Survival Study. Journal of Bone and Joint Surgery. 80:983-989. 1998
  9. Keys, G. et al. Analysis of First Forty Oxford Medial Unicompartmental Knee Replacements from a Small District Hospital in UK. Knee. 11:375-377. 2004.
  10. Rajasekhar, C. et al. Unicompartmental Knee Arthroplasty. 2-to12-year Results in a Community Hospital. Journal of Bone and Joint Surgery Br. 86:983-985. 2004.
  11. Price AJ, Svard U.:A second decade lifetable survival analysis of the Oxford unicompartmental knee arthroplasty. Clin Orthop RelatRes. 2011 Jan; 469(1): 174-9
  12. Emerson RH Jr, Higgins LL. Unicompartmental knee arthroplasty with the Oxford prosthesis in patients with medial compartment arthritis. J Bone Joint Surg Am. 2008 Jan; 90(1): 118-22.
  13. Svard, U. and Price, A. Oxford Medial 1. Unicompartmental Knee Arthroplasty. A Survival Analysis of an Independent Series. Journal of Bone and Joint Surgery Br. 83:191-194. 2001.
  14. Price, A. et al. Long-term Clinical Results of the Medial Oxford Unicompartmental Knee Arthroplasty. Clinical Orthopedics and Related Research. 435:171-180. 2005
  15. Cobb, JP, et al. Unicondylar knee arthroplasty in ht eUK National Health Service: An analysis of candidacy, outcome and cost efficacy. ScienceDirect. TheKnee 16.473-478. 2009
  16. Brown, NM, et al. Total Knee Arthroplasty Has Higher Postoperative Morbidity Than Unicompartmental Knee Arthroplasty: A Multicenter Analysis. The Journal of Arthroplasty. (2012)
  17. Robertsson, O, et al. Use of unicompartmental instead of tricompartmental prostheses for unicompartmental arthrosis in the knee is a cost effective alternative. Acta Orthrop Scand. (1999); 70(2): 170-175.